Malegra is a medication used to treat erectile dysfunction that contains sildenafil as its active salt. Sildenafil is an inhibitor of phosphodiesterase type 5 (PDE5), which helps men achieve and sustain an erection during sexual activity. By blocking PDE5, sildenafil helps raise cyclic Guanosine Monophosphate (cGMP) levels, which relax blood vessels and improve blood flow to the penis, enabling men to achieve an erection when they are aroused or sexually stimulated.
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